Items where Subject is "Subjects > Nutrition"

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2023

Article Subjects > Nutrition Europe University of Atlantic > Research > Scientific Production
Ibero-american International University > Research > Scientific Production
Universidad Internacional do Cuanza > Research > Scientific Production
Abierto Inglés There is growing evidence that Alzheimer’s disease (AD) can be prevented by reducing risk factors involved in its pathophysiology. Food-derived bioactive molecules can help in the prevention and reduction of the progression of AD. Honey, a good source of antioxidants and bioactive molecules, has been tied to many health benefits, including those from neurological origin. Monofloral avocado honey (AH) has recently been characterized but its biomedical properties are still unknown. The aim of this study is to further its characterization, focusing on the phenolic profile. Moreover, its antioxidant capacity was assayed both in vitro and in vivo. Finally, a deep analysis on the pathophysiological features of AD such as oxidative stress, amyloid-β aggregation, and protein-tau-induced neurotoxicity were evaluated by using the experimental model C. elegans. AH exerted a high antioxidant capacity in vitro and in vivo. No toxicity was found in C. elegans at the dosages used. AH prevented ROS accumulation under AAPH-induced oxidative stress. Additionally, AH exerted a great anti-amyloidogenic capacity, which is relevant from the point of view of AD prevention. AH exacerbated the locomotive impairment in a C. elegans model of tauopathy, although the real contribution of AH remains unclear. The mechanisms under the observed effects might be attributed to an upregulation of daf-16 as well as to a strong ROS scavenging activity. These results increase the interest to study the biomedical applications of AH; however, more research is needed to deepen the mechanisms under the observed effects metadata Romero-Márquez, Jose M. and Navarro-Hortal, María D. and Orantes, Francisco J. and Esteban-Muñoz, Adelaida and Mazas Pérez-Oleaga, Cristina and Battino, Maurizio and Sánchez-González, Cristina and Rivas-García, Lorenzo and Giampieri, Francesca and Quiles, José L. and Forbes-Hernandez, Tamara Y. mail UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, cristina.mazas@uneatlantico.es, maurizio.battino@uneatlantico.es, UNSPECIFIED, UNSPECIFIED, francesca.giampieri@uneatlantico.es, jose.quiles@uneatlantico.es, tamara.forbes@unini.edu.mx (2023) In Vivo Anti-Alzheimer and Antioxidant Properties of Avocado (Persea americana Mill.) Honey from Southern Spain. Antioxidants, 12 (2). p. 404. ISSN 2076-3921

Article Subjects > Nutrition Europe University of Atlantic > Research > Scientific Production
Ibero-american International University > Research > Scientific Production
Universidad Internacional do Cuanza > Research > Scientific Production
Abierto Inglés Alzheimer’s Disease (AD) is the cause of around 60–70% of global cases of dementia and approximately 50 million people have been reported to suffer this disease worldwide. The leaves of olive trees (Olea europaea) are the most abundant by-products of the olive grove industry. These by-products have been highlighted due to the wide variety of bioactive compounds such as oleuropein (OLE) and hydroxytyrosol (HT) with demonstrated medicinal properties to fight AD. In particular, the olive leaf (OL), OLE, and HT reduced not only amyloid-β formation but also neurofibrillary tangles formation through amyloid protein precursor processing modulation. Although the isolated olive phytochemicals exerted lower cholinesterase inhibitory activity, OL demonstrated high inhibitory activity in the cholinergic tests evaluated. The mechanisms underlying these protective effects may be associated with decreased neuroinflammation and oxidative stress via NF-κB and Nrf2 modulation, respectively. Despite the limited research, evidence indicates that OL consumption promotes autophagy and restores loss of proteostasis, which was reflected in lower toxic protein aggregation in AD models. Therefore, olive phytochemicals may be a promising tool as an adjuvant in the treatment of AD. metadata Romero-Márquez, Jose M. and Forbes-Hernández, Tamara Y. and Navarro-Hortal, María D. and Quirantes-Piné, Rosa and Grosso, Giuseppe and Giampieri, Francesca and Lipari, Vivian and Sánchez-González, Cristina and Battino, Maurizio and Quiles, José L. mail UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, francesca.giampieri@uneatlantico.es, vivian.lipari@uneatlantico.es, UNSPECIFIED, maurizio.battino@uneatlantico.es, jose.quiles@uneatlantico.es (2023) Molecular Mechanisms of the Protective Effects of Olive Leaf Polyphenols against Alzheimer’s Disease. International Journal of Molecular Sciences, 24 (5). p. 4353. ISSN 1422-0067

Article Subjects > Nutrition Europe University of Atlantic > Research > Scientific Production
Ibero-american International University > Research > Scientific Production
Universidad Internacional do Cuanza > Research > Scientific Production
Cerrado Inglés Inflammatory bowel disease (IBD) patients are at substantially higher risk of colorectal cancer (CRC) and IBD-associated CRC accounts for roughly 10-15% of the annual mortality in IBD patients. IBD-related CRC also affects younger patients if compared with sporadic CRC, with a 5-year survival rate of 50%. Regardless of medical therapies, the persistent inflammation state characterizing IBD raises the risk for precancerous changes and CRC, with additional input from several elements including genetic and environmental risk factors, IBD-associated comorbidities, intestinal barrier disfunction, and gut microbiota modifications. It is well known that nutritional habits and dietary bioactive compounds can influence IBD-associated inflammation, microbiome abundance and composition, oxidative stress balance, and gut permeability. In addition, in the last years, results from broad epidemiological and experimental studies have associated certain foods or nutritional patterns with the risk of colorectal neoplasia. Here we review the possible role of nutrition in the prevention of IBD-related CRC, focusing specifically on human studies. In conclusion it emerges that nutritional interventions based on healthy, nutrient-dense dietary patterns characterized by a high intake of fiber, vegetables, fruit, Omega-3 PUFAs, and low amount of animal proteins, processed foods and alcohol, combined with probiotic supplementation have the potential of reducing IBD-activity and preventing the risk of IBD-related CRC through different mechanisms, suggesting that targeted nutritional interventions may represent a novel promising approach for the prevention and management of IBD-associated CRC. metadata Cassotta, Manuela and Cianciosi, Danila and De Giuseppe, Rachele and Navarro-Hortal, Maria Dolores and Diaz, Yasmany Armas and Forbes-Hernández, Tamara Yuliett and Tutusaus, Kilian and Pascual Barrera, Alina Eugenia and Grosso, Giuseppe and Xiao, Jianbo and Battino, Maurizio and Giampieri, Francesca mail manucassotta@gmail.com, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, kilian.tutusaus@uneatlantico.es, alina.pascual@unini.edu.mx, UNSPECIFIED, UNSPECIFIED, maurizio.battino@uneatlantico.es, francesca.giampieri@uneatlantico.es (2023) Possible role of nutrition in the prevention of Inflammatory Bowel Disease-related colorectal cancer: a focus on human studies. Nutrition. p. 111980. ISSN 08999007

Article Subjects > Biomedicine
Subjects > Engineering
Subjects > Nutrition
Europe University of Atlantic > Research > Scientific Production
Ibero-american International University > Research > Scientific Production
Ibero-american International University > Research > Scientific Production
Universidad Internacional do Cuanza > Research > Scientific Production
Cerrado Inglés Obesity and overweight has increased in the last year and has become a pandemic disease, the result of sedentary lifestyles and unhealthy diets rich in sugars, refined starches, fats and calories. Machine learning (ML) has proven to be very useful in the scientific community, especially in the health sector. With the aim of providing useful tools to help nutritionists and dieticians, research focused on the development of ML and Deep Learning (DL) algorithms and models is searched in the literature. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) protocol has been used, a very common technique applied to carry out revisions. In our proposal, 17 articles have been filtered in which ML and DL are applied in the prediction of diseases, in the delineation of treatment strategies, in the improvement of personalized nutrition and more. Despite expecting better results with the use of DL, according to the selected investigations, the traditional methods are still the most used and the yields in both cases fluctuate around positive values, conditioned by the databases (transformed in each case) to a greater extent than by the artificial intelligence paradigm used. Conclusions: An important compilation is provided for the literature in this area. ML models are time-consuming to clean data, but (like DL) they allow automatic modeling of large volumes of data which makes them superior to traditional statistics. metadata Ferreras, Antonio and Sumalla Cano, Sandra and Martínez-Licort, Rosmeri and Elío Pascual, Iñaki and Tutusaus, Kilian and Prola, Thomas and Vidal Mazón, Juan Luis and Sahelices, Benjamín and de la Torre Díez, Isabel mail UNSPECIFIED, sandra.sumalla@uneatlantico.es, UNSPECIFIED, inaki.elio@uneatlantico.es, kilian.tutusaus@uneatlantico.es, thomas.prola@uneatlantico.es, juanluis.vidal@uneatlantico.es, UNSPECIFIED, UNSPECIFIED (2023) Systematic Review of Machine Learning applied to the Prediction of Obesity and Overweight. Journal of Medical Systems, 47 (1). ISSN 1573-689X

2022

Article Subjects > Nutrition Europe University of Atlantic > Research > Scientific Production
Ibero-american International University > Research > Scientific Production
Universidad Internacional do Cuanza > Research > Scientific Production
Abierto Inglés Age-related macular degeneration (AMD) is a serious degenerative disease affecting the eyes, and is the main cause of severe vision loss among people >55 years of age in developed countries. Its onset and progression have been associated with several genetic and lifestyle factors, with diet appearing to play a pivotal role in the latter. In particular, dietary eating patterns rich in plant foods have been shown to lower the risk of developing the disease, and to decrease the odds of progressing to more advanced stages in individuals already burdened with early AMD. We systematically reviewed the literature to analyse the relationship between the adherence to a Mediterranean diet, a mainly plant-based dietary pattern, and the onset/progression of AMD. Eight human observational studies were analysed. Despite some differences, they consistently indicate that higher adherence to a Mediterranean eating pattern lowers the odds of developing AMD and decreases the risk of progression to more advanced stages of the disease, establishing the way for preventative measures emphasizing dietary patterns rich in plant-foods metadata Gastaldello, Annalisa and Giampieri, Francesca and Quiles, José L. and Navarro-Hortal, María D. and Aparicio Obregón, Silvia and García Villena, Eduardo and Tutusaus, Kilian and De Giuseppe, Rachele and Grosso, Giuseppe and Cianciosi, Danila and Forbes-Hernández, Tamara Y. and Nabavi, Seyed M. and Battino, Maurizio mail UNSPECIFIED, francesca.giampieri@uneatlantico.es, jose.quiles@uneatlantico.es, UNSPECIFIED, silvia.aparicio@uneatlantico.es, eduardo.garcia@uneatlantico.es, kilian.tutusaus@uneatlantico.es, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, maurizio.battino@uneatlantico.es (2022) Adherence to the Mediterranean-Style Eating Pattern and Macular Degeneration: A Systematic Review of Observational Studies. Nutrients, 14 (10). p. 2028. ISSN 2072-6643

Article Subjects > Biomedicine
Subjects > Nutrition
Europe University of Atlantic > Research > Scientific Production
Fundación Universitaria Internacional de Colombia > Research > Scientific Production
Ibero-american International University > Research > Scientific Production
Ibero-american International University > Research > Scientific Production
Universidad Internacional do Cuanza > Research > Scientific Production
Cerrado Inglés Cactus has been used in traditional folk medicine because of its role in treating a number of diseases and conditions. Prickly pear fruit is an excellent source of secondary metabolites (i.e., betalains, flavonoids, and ascorbic acid) with health-promoting properties against many common human diseases, including diabetes, hypertension, hypercholesterolemia, rheumatic pain, gastric mucosa diseases and asthma. In addition, prickly pears are potential candidates for the development of low-cost functional foods because they grow with low water requirements in arid regions of the world. This review describes the main bioactive compounds found in this fruit and shows the in vitro and some clinical studies about the fruit of most important cactus (Opuntia ficus-indica) and its relationship with some chronic diseases. Even though a lot of effort have been done to study the relationship between this fruit and the human health, more studies on Opuntia ficus-indica could help better understand its pharmacological mechanism of action to provide clear scientific evidence to explain its traditional uses, and to identify its therapeutic potential in other diseases. metadata Armas Diaz, Yasmany and Machì, Michele and Salinari, Alessia and Mazas Pérez-Oleaga, Cristina and Martínez López, Nohora Milena and Briones Urbano, Mercedes and Cianciosi, Danila mail UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, cristina.mazas@uneatlantico.es, nohora.martinez@uneatlantico.es, mercedes.briones@uneatlantico.es, UNSPECIFIED (2022) Prickly pear fruits from "Opuntia ficus-indica" varieties as a source of potential bioactive compounds in the Mediterranean diet. Mediterranean Journal of Nutrition and Metabolism, 15 (4). pp. 581-592. ISSN 1973798X

This list was generated on Sun Jun 4 23:40:18 2023 UTC.

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Deep Learning-Based Real Time Defect Detection for Optimization of Aircraft Manufacturing and Control Performance

Monitoring tool conditions and sub-assemblies before final integration is essential to reducing processing failures and improving production quality for manufacturing setups. This research study proposes a real-time deep learning-based framework for identifying faulty components due to malfunctioning at different manufacturing stages in the aerospace industry. It uses a convolutional neural network (CNN) to recognize and classify intermediate abnormal states in a single manufacturing process. The manufacturing process for aircraft factory products comprises different phases; analyzing the components after the integration is labor-intensive and time-consuming, which often puts the company’s stake at high risk. To overcome these challenges, the proposed AI-based system can perform inspection and defect detection and alleviate the probability of components’ needing to be re-manufacturing after being assembled. In addition, it analyses the impact value, i.e., rework delays and costs, of manufacturing processes using a statistical process control tool on real-time data for various manufactured components. Defects are detected and classified using the CNN and teachable machine in the single manufacturing process during the initial stage prior to assembling the components. The results show the significance of the proposed approach in improving operational cost management and reducing rework-induced delays. Ground tests are conducted to calculate the impact value followed by the air tests of the final assembled aircraft. The statistical results indicate a 52.88% and 34.32% reduction in time delays and total cost, respectively.

Producción Científica

Imran Shafi mail , Muhammad Fawad Mazhar mail , Anum Fatima mail , Roberto Marcelo Álvarez mail roberto.alvarez@uneatlantico.es, Yini Airet Miró Vera mail yini.miro@uneatlantico.es, Julio César Martínez Espinosa mail ulio.martinez@unini.edu.mx, Imran Ashraf mail ,

Shafi

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Systematic Review of Machine Learning applied to the Prediction of Obesity and Overweight

Obesity and overweight has increased in the last year and has become a pandemic disease, the result of sedentary lifestyles and unhealthy diets rich in sugars, refined starches, fats and calories. Machine learning (ML) has proven to be very useful in the scientific community, especially in the health sector. With the aim of providing useful tools to help nutritionists and dieticians, research focused on the development of ML and Deep Learning (DL) algorithms and models is searched in the literature. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) protocol has been used, a very common technique applied to carry out revisions. In our proposal, 17 articles have been filtered in which ML and DL are applied in the prediction of diseases, in the delineation of treatment strategies, in the improvement of personalized nutrition and more. Despite expecting better results with the use of DL, according to the selected investigations, the traditional methods are still the most used and the yields in both cases fluctuate around positive values, conditioned by the databases (transformed in each case) to a greater extent than by the artificial intelligence paradigm used. Conclusions: An important compilation is provided for the literature in this area. ML models are time-consuming to clean data, but (like DL) they allow automatic modeling of large volumes of data which makes them superior to traditional statistics.

Producción Científica

Antonio Ferreras mail , Sandra Sumalla Cano mail sandra.sumalla@uneatlantico.es, Rosmeri Martínez-Licort mail , Iñaki Elío Pascual mail inaki.elio@uneatlantico.es, Kilian Tutusaus mail kilian.tutusaus@uneatlantico.es, Thomas Prola mail thomas.prola@uneatlantico.es, Juan Luis Vidal Mazón mail juanluis.vidal@uneatlantico.es, Benjamín Sahelices mail , Isabel de la Torre Díez mail ,

Ferreras

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Integration of Sustainable Criteria in the Development of a Proposal for an Online Postgraduate Program in the Projects Area

Regulatory dispersion and a utilitarian use of sustainability deepen the gap within the teaching–learning process and limit the introduction of sustainable criteria in organizations through projects. The objective of this research consisted in developing a sustainable and holistic educational proposal for an online postgraduate program belonging to the Universidad Europea del Atlántico (UNEATLANTICO) within the field of projects. The proposal was based on the instrumentalization of a model comprised of national and international bibliographic references, resulting in a sustainability guide with significant improvements in relation to the reference standard par excellence: ISO 26000:2010. This guide formed the basis of a sustainability management plan, which was key in the project methodology and during the development of sustainable objectives and descriptors for each of the subjects. Lastly, the entities, attributes, and cardinal relationships were established for the development of a physical model used to facilitate the management of all this information within a SQL database. The rigor when determining the educational program, as well as the subsequent analysis of results as supported by the literature review, presupposes the application of this methodology toward other multidisciplinary programs contributing to the adoption of good sustainability practices within the educational field

Producción Científica

Mónica Gracia Villar mail monica.gracia@uneatlantico.es, Roberto Marcelo Álvarez mail roberto.alvarez@uneatlantico.es, Santiago Brie mail santiago.brie@uneatlantico.es, Yini Airet Miró Vera mail yini.miro@uneatlantico.es, Eduardo García Villena mail eduardo.garcia@uneatlantico.es,

Gracia Villar

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Conformidade legal no ensino superior em Angola: criação de um instrumento de gestão das obrigações legais

O quadro legal angolano para o subsistema de ensino superior cresceu significativamente desde 2009, um crescimento que tem estado a visar o aumento da transparência e da qualidade dos processos educacionais nas instituições de ensino superior (IES) angolanas. Entretanto, a qualidade do ensino superior em Angola não sofreu melhorias significativas por não se estar a cumprir escrupulosamente com o quadro legal de forma sistemática, o que tem resultado em encerramentos de cursos e instituições do ensino superior. Este artigo tem como objetivo principal desenvolver um instrumento de auto- monitorização da conformidade legal que pode ajudar as IES angolanas a tirarem mais proveito do quadro legal do ensino superior. Por intermédio de um levantamento bibliográfico das leis relevantes ao ensino superior em Angola, a identificação de obrigações legais nestas e o desenvolvimento de uma série de tabelas de verificação de conformidade, este estudo apresenta uma checklist de auto verificação da conformidade entre o funcionamento das instituições do ensino superior e o quadro legal relevante ao ensino superior em Angola. Pela utilização deste instrumento, foi possível dissecar as obrigações legais em requisitos ou critérios. Foi também possível estabelecer três graus de conformidade legal, nomeadamente: total, parcial e nenhuma. Notou-se, de igual forma, a existência de um total de 83 obrigações legais das instituições do ensino superior em Angola, sendo os regulamentos e as normas as fontes do maior número de obrigações. Destes, existem entre cinco a quinze requisitos legais por obrigação, perfazendo um volume enorme de requisitos legais com os quais as IES em Angola devem mostrar conformidade legal. A aplicação da checklist permite a gestão desse leque diverso e numeroso de requisitos específicos legais. São sugeridas várias medidas complementares ao quadro legal que devem ser implementadas em Angola com o intuito de se criar uma cultura de conformidade legal no ensino superior, promovendo-se, deste modo, a sua qualidade.

Produção científica

João Manuel da Costa Canoquena mail joao.canoquena@unic.co.ao, María Elena Castro Rodríguez mail maria.rodriguez@unic.co.ao, Yanisleidy Moreira Cabrera mail yanisleidy.cabrera@unic.co.ao,

da Costa Canoquena

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Contextual Urdu Lemmatization Using Recurrent Neural Network Models

In the field of natural language processing, machine translation is a colossally developing research area that helps humans communicate more effectively by bridging the linguistic gap. In machine translation, normalization and morphological analyses are the first and perhaps the most important modules for information retrieval (IR). To build a morphological analyzer, or to complete the normalization process, it is important to extract the correct root out of different words. Stemming and lemmatization are techniques commonly used to find the correct root words in a language. However, a few studies on IR systems for the Urdu language have shown that lemmatization is more effective than stemming due to infixes found in Urdu words. This paper presents a lemmatization algorithm based on recurrent neural network models for the Urdu language. However, lemmatization techniques for resource-scarce languages such as Urdu are not very common. The proposed model is trained and tested on two datasets, namely, the Urdu Monolingual Corpus (UMC) and the Universal Dependencies Corpus of Urdu (UDU). The datasets are lemmatized with the help of recurrent neural network models. The Word2Vec model and edit trees are used to generate semantic and syntactic embedding. Bidirectional long short-term memory (BiLSTM), bidirectional gated recurrent unit (BiGRU), bidirectional gated recurrent neural network (BiGRNN), and attention-free encoder–decoder (AFED) models are trained under defined hyperparameters. Experimental results show that the attention-free encoder-decoder model achieves an accuracy, precision, recall, and F-score of 0.96, 0.95, 0.95, and 0.95, respectively, and outperforms existing models

Producción Científica

Rabab Hafeez mail , Muhammad Waqas Anwar mail , Muhammad Hasan Jamal mail , Tayyaba Fatima mail , Julio César Martínez Espinosa mail ulio.martinez@unini.edu.mx, Luis Alonso Dzul López mail luis.dzul@uneatlantico.es, Ernesto Bautista Thompson mail ernesto.bautista@unini.edu.mx, Imran Ashraf mail ,

Hafeez