Items where Subject is "Subjects > Nutrition"

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2024

Article Subjects > Biomedicine
Subjects > Engineering
Subjects > Nutrition
Europe University of Atlantic > Research > Scientific Production
Ibero-american International University > Research > Scientific Production
Universidad Internacional do Cuanza > Research > Articles and books
Abierto Inglés Background and objectives: As microbes are developing resistance to antibiotics, natural, botanical drugs or traditional herbal medicine are presently being studied with an eye of great curiosity and hope. Hence, complementary and alternative treatments for uncomplicated pelvic inflammatory disease (uPID) are explored for their efficacy. Therefore, this study determined the therapeutic efficacy and safety of Sesamum indicum Linn seeds with Rosa damascena Mill Oil in uPID with standard control. Additionally, we analyzed the data with machine learning. Materials and methods: We included 60 participants in a double-blind, double-dummy, randomized standard-controlled study. Participants in the Sesame and Rose oil group (SR group) (n = 30) received 14 days course of black sesame powder (5 gm) mixed with rose oil (10 mL) per vaginum at bedtime once daily plus placebo capsules orally. The standard group (SC), received doxycycline 100 mg twice and metronidazole 400 mg thrice orally plus placebo per vaginum for the same duration. The primary outcome was a clinical cure at post-intervention for visual analogue scale (VAS) for lower abdominal pain (LAP), and McCormack pain scale (McPS) for abdominal-pelvic tenderness. The secondary outcome included white blood cells (WBC) cells in the vaginal wet mount test, safety profile, and health-related quality of life assessed by SF-12. In addition, we used AdaBoost (AB), Naïve Bayes (NB), and Decision Tree (DT) classifiers in this study to analyze the experimental data. Results: The clinical cure for LAP and McPS in the SR vs SC group was 82.85% vs 81.48% and 83.85% vs 81.60% on Day 15 respectively. On Day 15, pus cells less than 10 in the SR vs SC group were 86.6% vs 76.6% respectively. No adverse effects were reported in both groups. The improvement in total SF-12 score on Day 30 for the SR vs SC group was 82.79% vs 80.04% respectively. In addition, our Naive Bayes classifier based on the leave-one-out model achieved the maximum accuracy (68.30%) for the classification of both groups of uPID. Conclusion: We concluded that the SR group is cost-effective, safer, and efficacious for curing uPID. Proposed alternative treatment (test drug) could be a substitute of standard drug used for Female genital tract infections. metadata Sumbul, X. and Sultana, Arshiya and Heyat, Md Belal Bin and Rahman, Khaleequr and Akhtar, Faijan and Parveen, Saba and Briones Urbano, Mercedes and Lipari, Vivian and De la Torre Díez, Isabel and Khan, Azmat Ali and Malik, Abdul mail UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, mercedes.briones@uneatlantico.es, vivian.lipari@uneatlantico.es, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED (2024) Efficacy and classification of Sesamum indicum linn seeds with Rosa damascena mill oil in uncomplicated pelvic inflammatory disease using machine learning. Frontiers in Chemistry, 12. ISSN 2296-2646

Article Subjects > Nutrition Europe University of Atlantic > Research > Scientific Production
Ibero-american International University > Research > Scientific Production
Universidad Internacional do Cuanza > Research > Articles and books
Abierto Inglés In the last decades, the world population and demand for any kind of product have grown exponentially. The rhythm of production to satisfy the request of the population has become unsustainable and the concept of the linear economy, introduced after the Industrial Revolution, has been replaced by a new economic approach, the circular economy. In this new economic model, the concept of “the end of life” is substituted by the concept of restoration, providing a new life to many industrial wastes. Leaves are a by-product of several agricultural cultivations. In recent years, the scientific interest regarding leaf biochemical composition grew, recording that plant leaves may be considered an alternative source of bioactive substances. Plant leaves’ main bioactive compounds are similar to those in fruits, i.e., phenolic acids and esters, flavonols, anthocyanins, and procyanidins. Bioactive compounds can positively influence human health; in fact, it is no coincidence that the leaves were used by our ancestors as a natural remedy for various pathological conditions. Therefore, leaves can be exploited to manufacture many products in food (e.g., being incorporated in food formulations as natural antioxidants, or used to create edible coatings or films for food packaging), cosmetic and pharmaceutical industries (e.g., promising ingredients in anti-aging cosmetics such as oils, serums, dermatological creams, bath gels, and other products). This review focuses on the leaves’ main bioactive compounds and their beneficial health effects, indicating their applications until today to enhance them as a harvesting by-product and highlight their possible reuse for new potential healthy products. metadata Regolo, Lucia and Giampieri, Francesca and Battino, Maurizio and Armas Diaz, Yasmany and Mezzetti, Bruno and Elexpuru Zabaleta, Maria and Mazas Pérez-Oleaga, Cristina and Tutusaus, Kilian and Mazzoni, Luca mail UNSPECIFIED, francesca.giampieri@uneatlantico.es, maurizio.battino@uneatlantico.es, UNSPECIFIED, UNSPECIFIED, maria.elexpuru@uneatlantico.es, cristina.mazas@uneatlantico.es, kilian.tutusaus@uneatlantico.es, UNSPECIFIED (2024) From by-products to new application opportunities: the enhancement of the leaves deriving from the fruit plants for new potential healthy products. Frontiers in Nutrition, 11. ISSN 2296-861X

Article Subjects > Nutrition Europe University of Atlantic > Research > Scientific Production
Fundación Universitaria Internacional de Colombia > Research > Scientific Production
Ibero-american International University > Research > Scientific Production
Ibero-american International University > Research > Scientific Production
Universidad Internacional do Cuanza > Research > Articles and books
Abierto Inglés Much of nutrition research has been conventionally based on the use of simplistic in vitro systems or animal models, which have been extensively employed in an effort to better understand the relationships between diet and complex diseases as well as to evaluate food safety. Although these models have undeniably contributed to increase our mechanistic understanding of basic biological processes, they do not adequately model complex human physiopathological phenomena, creating concerns about the translatability to humans. During the last decade, extraordinary advancement in stem cell culturing, three-dimensional cell cultures, sequencing technologies, and computer science has occurred, which has originated a wealth of novel human-based and more physiologically relevant tools. These tools, also known as “new approach methodologies,” which comprise patient-derived organoids, organs-on-chip, multi-omics approach, along with computational models and analysis, represent innovative and exciting tools to forward nutrition research from a human-biology-oriented perspective. After considering some shortcomings of conventional in vitro and vivo approaches, here we describe the main novel available and emerging tools that are appropriate for designing a more human-relevant nutrition research. Our aim is to encourage discussion on the opportunity to explore innovative paths in nutrition research and to promote a paradigm-change toward a more human biology-focused approach to better understand human nutritional pathophysiology, to evaluate novel food products, and to develop more effective targeted preventive or therapeutic strategies while helping in reducing the number and replacing animals employed in nutrition research. metadata Cassotta, Manuela and Cianciosi, Danila and Elexpuru Zabaleta, Maria and Elío Pascual, Iñaki and Sumalla Cano, Sandra and Giampieri, Francesca and Battino, Maurizio mail manucassotta@gmail.com, UNSPECIFIED, maria.elexpuru@uneatlantico.es, inaki.elio@uneatlantico.es, sandra.sumalla@uneatlantico.es, francesca.giampieri@uneatlantico.es, maurizio.battino@uneatlantico.es (2024) Human‐based new approach methodologies to accelerate advances in nutrition research. Food Frontiers. pp. 1-32. ISSN 2643-8429

Article Subjects > Biomedicine
Subjects > Nutrition
Europe University of Atlantic > Research > Scientific Production
Ibero-american International University > Research > Scientific Production
Ibero-american International University > Research > Scientific Production
Universidad Internacional do Cuanza > Research > Articles and books
University of La Romana > Research > Scientific Production
Abierto Inglés Isoflavones are a group of (poly)phenols, also defined as phytoestrogens, with chemical structures comparable with estrogen, that exert weak estrogenic effects. These phytochemical compounds have been targeted for their proven antioxidant and protective effects. Recognizing the increasing prevalence of cardiovascular diseases (CVD), there is a growing interest in understanding the potential cardiovascular benefits associated with these phytochemical compounds. Gut microbiota may play a key role in mediating the effects of isoflavones on vascular and endothelial functions, as it is directly implicated in isoflavones metabolism. The findings from randomized clinical trials indicate that isoflavone supplementation may exert putative effects on vascular biomarkers among healthy individuals, but not among patients affected by cardiometabolic disorders. These results might be explained by the enzymatic transformation to which isoflavones are subjected by the gut microbiota, suggesting that a diverse composition of the microbiota may determine the diverse bioavailability of these compounds. Specifically, the conversion of isoflavones in equol—a microbiota-derived metabolite—seems to differ between individuals. Further studies are needed to clarify the intricate molecular mechanisms behind these contrasting results. metadata Laudani, Samuele and Godos, Justyna and Romano, Giovanni Luca and Gozzo, Lucia and Di Domenico, Federica Martina and Dominguez Azpíroz, Irma and Martínez Díaz, Raquel and Giampieri, Francesca and Quiles, José L. and Battino, Maurizio and Drago, Filippo and Galvano, Fabio and Grosso, Giuseppe mail UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, irma.dominguez@unini.edu.mx, raquel.martinez@uneatlantico.es, francesca.giampieri@uneatlantico.es, jose.quiles@uneatlantico.es, maurizio.battino@uneatlantico.es, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED (2024) Isoflavones Effects on Vascular and Endothelial Outcomes: How Is the Gut Microbiota Involved? Pharmaceuticals, 17 (2). p. 236. ISSN 1424-8247

Article Subjects > Nutrition Europe University of Atlantic > Research > Scientific Production
Ibero-american International University > Research > Scientific Production
Ibero-american International University > Research > Scientific Production
Universidad Internacional do Cuanza > Research > Articles and books
University of La Romana > Research > Scientific Production
Abierto Inglés The prevalence of sleep disorders, characterized by issues with quality, timing, and sleep duration is increasing globally. Among modifiable risk factors, diet quality has been suggested to influence sleep features. The Mediterranean diet is considered a landmark dietary pattern in terms of quality and effects on human health. However, dietary habits characterized by this cultural heritage should also be considered in the context of overall lifestyle behaviors, including sleep habits. This study aimed to systematically revise the literature relating to adherence to the Mediterranean diet and sleep features in observational studies. The systematic review comprised 23 reports describing the relation between adherence to the Mediterranean diet and different sleep features, including sleep quality, sleep duration, daytime sleepiness, and insomnia symptoms. The majority of the included studies were conducted in the Mediterranean basin and reported a significant association between a higher adherence to the Mediterranean diet and a lower likelihood of having poor sleep quality, inadequate sleep duration, excessive daytime sleepiness or symptoms of insomnia. Interestingly, additional studies conducted outside the Mediterranean basin showed a relationship between the adoption of a Mediterranean-type diet and sleep quality, suggesting that biological mechanisms sustaining such an association may exist. In conclusion, current evidence suggests a relationship between adhering to the Mediterranean diet and overall sleep quality and different sleep parameters. The plausible bidirectional association should be further investigated to understand whether the promotion of a healthy diet could be used as a tool to improve sleep quality. metadata Godos, Justyna and Ferri, Raffaele and Lanza, Giuseppe and Caraci, Filippo and Rojas Vistorte, Angel Olider and Yélamos Torres, Vanessa and Grosso, Giuseppe and Castellano, Sabrina mail UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, angel.rojas@uneatlantico.es, vanessa.yelamos@funiber.org, UNSPECIFIED, UNSPECIFIED (2024) Mediterranean Diet and Sleep Features: A Systematic Review of Current Evidence. Nutrients, 16 (2). p. 282. ISSN 2072-6643

Article Subjects > Nutrition Europe University of Atlantic > Research > Scientific Production
Ibero-american International University > Research > Scientific Production
Ibero-american International University > Research > Scientific Production
Universidad Internacional do Cuanza > Research > Articles and books
University of La Romana > Research > Scientific Production
Abierto Inglés The purpose of the study is to assess the risk of developing general eating disorders (ED), anorexia nervosa (AN), and bulimia nervosa (BN), as well as to examine the effects of gender, academic year, place of residence, faculty, and diet quality on that risk. Over two academic years, 129 first- and fourth-year Uneatlántico students were included in an observational descriptive study. The self-administered tests SCOFF, EAT-26, and BITE were used to determine the participants’ risk of developing ED. The degree of adherence to the Mediterranean diet (MD) was used to evaluate the quality of the diet. Data were collected at the beginning (T1) and at the end (T2) of the academic year. The main results were that at T1, 34.9% of participants were at risk of developing general ED, AN 3.9%, and BN 16.3%. At T2, these percentages were 37.2%, 14.7%, and 8.5%, respectively. At T2, the frequency of general ED in the female group was 2.5 times higher (OR: 2.55, 95% CI: 1.22–5.32, p = 0.012). The low-moderate adherence to the MD students’ group was 0.92 times less frequent than general ED at T2 (OR: 0.921, 95%CI: 0.385–2.20, p < 0.001). The most significant risk factor for developing ED is being a female in the first year of university. Moreover, it appears that the likelihood of developing ED generally increases during the academic year. metadata Eguren García, Imanol and Sumalla Cano, Sandra and Conde González, Sandra and Vila-Martí, Anna and Briones Urbano, Mercedes and Martínez Díaz, Raquel and Elío Pascual, Iñaki mail imanol.eguren@uneatlantico.es, sandra.sumalla@uneatlantico.es, UNSPECIFIED, UNSPECIFIED, mercedes.briones@uneatlantico.es, raquel.martinez@uneatlantico.es, inaki.elio@uneatlantico.es (2024) Risk Factors for Eating Disorders in University Students: The RUNEAT Study. Healthcare, 12 (9). p. 942. ISSN 2227-9032

2023

Other Subjects > Biomedicine
Subjects > Engineering
Subjects > Nutrition
Europe University of Atlantic > Research > Projects I+D+I
Universidad Internacional do Cuanza > Research > Projects I+D+I
Cerrado Inglés CLINICALSIM is a capability building project targeted to Angola Higher Education Institutions with the aim of improving the practical training of nurses. Nurses are in the focus of health challenges in Angola and they are highly demanded in healthcare, meanwhile their practical competencies are considered as a critical issue. The consortium pursues filling the gap in practical skills (decision-making, interpersonal skills, human nutrition) and promoting HEIs social commitment. We will take advantage of simulation suites and multimedia digital tools to deploy experiential learnings and to promote a Community Service/Service-Learning into the universities. The experiential learning will take place in three different scenarios: simulation suites, digital multimedia and real patients. A reflective practice methodology with a debriefing process will be followed. In the context of Service-Learning, we also introduce the social aim of CLINICALSIM and we appoint special considerations to individuals with socio-economic obstacles and health problems and the promotion of better nutrition habits. CLINICALSIM es un proyecto de desarrollo de capacidades dirigido a las Instituciones de Educación Superior (IES) de Angola con el objetivo de mejorar la formación práctica de los profesionales de la enfermería. Este colectivo se encuentra en el centro de los retos sanitarios en Angola y es muy solicitado en la asistencia sanitaria, mientras que sus competencias prácticas se consideran una cuestión crítica. El consorcio pretende llenar el vacío existente en las habilidades prácticas (toma de decisiones, habilidades interpersonales, nutrición humana) y promover el compromiso social de las IES. Se aprovecharán las suites de simulación y las herramientas digitales multimedia para desplegar aprendizajes experienciales y promover un Servicio Comunitario/Aprendizaje-Servicio en las universidades. El aprendizaje experiencial se llevará a cabo en tres escenarios diferentes: salas de simulación, multimedia digital y pacientes reales, siguiendo una metodología de práctica reflexiva con un proceso de debriefing. En el contexto del Aprendizaje-Servicio, también se introduce el objetivo social de CLINICALSIM y se nombran consideraciones especiales a individuos con obstáculos socioeconómicos y problemas de salud y la promoción de mejores hábitos de nutrición. metadata UNSPECIFIED mail UNSPECIFIED (2023) CLINICALSIM: Clinical simulation practice-based learning in nursing. Repositorio de la Universidad.

Article Subjects > Nutrition Europe University of Atlantic > Research > Scientific Production
Ibero-american International University > Research > Scientific Production
Universidad Internacional do Cuanza > Research > Articles and books
Abierto Inglés There is growing evidence that Alzheimer’s disease (AD) can be prevented by reducing risk factors involved in its pathophysiology. Food-derived bioactive molecules can help in the prevention and reduction of the progression of AD. Honey, a good source of antioxidants and bioactive molecules, has been tied to many health benefits, including those from neurological origin. Monofloral avocado honey (AH) has recently been characterized but its biomedical properties are still unknown. The aim of this study is to further its characterization, focusing on the phenolic profile. Moreover, its antioxidant capacity was assayed both in vitro and in vivo. Finally, a deep analysis on the pathophysiological features of AD such as oxidative stress, amyloid-β aggregation, and protein-tau-induced neurotoxicity were evaluated by using the experimental model C. elegans. AH exerted a high antioxidant capacity in vitro and in vivo. No toxicity was found in C. elegans at the dosages used. AH prevented ROS accumulation under AAPH-induced oxidative stress. Additionally, AH exerted a great anti-amyloidogenic capacity, which is relevant from the point of view of AD prevention. AH exacerbated the locomotive impairment in a C. elegans model of tauopathy, although the real contribution of AH remains unclear. The mechanisms under the observed effects might be attributed to an upregulation of daf-16 as well as to a strong ROS scavenging activity. These results increase the interest to study the biomedical applications of AH; however, more research is needed to deepen the mechanisms under the observed effects metadata Romero-Márquez, Jose M. and Navarro-Hortal, María D. and Orantes, Francisco J. and Esteban-Muñoz, Adelaida and Mazas Pérez-Oleaga, Cristina and Battino, Maurizio and Sánchez-González, Cristina and Rivas-García, Lorenzo and Giampieri, Francesca and Quiles, José L. and Forbes-Hernandez, Tamara Y. mail UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, cristina.mazas@uneatlantico.es, maurizio.battino@uneatlantico.es, UNSPECIFIED, UNSPECIFIED, francesca.giampieri@uneatlantico.es, jose.quiles@uneatlantico.es, tamara.forbes@unini.edu.mx (2023) In Vivo Anti-Alzheimer and Antioxidant Properties of Avocado (Persea americana Mill.) Honey from Southern Spain. Antioxidants, 12 (2). p. 404. ISSN 2076-3921

Article Subjects > Nutrition Europe University of Atlantic > Research > Scientific Production
Ibero-american International University > Research > Scientific Production
Universidad Internacional do Cuanza > Research > Articles and books
Abierto Inglés Alzheimer’s Disease (AD) is the cause of around 60–70% of global cases of dementia and approximately 50 million people have been reported to suffer this disease worldwide. The leaves of olive trees (Olea europaea) are the most abundant by-products of the olive grove industry. These by-products have been highlighted due to the wide variety of bioactive compounds such as oleuropein (OLE) and hydroxytyrosol (HT) with demonstrated medicinal properties to fight AD. In particular, the olive leaf (OL), OLE, and HT reduced not only amyloid-β formation but also neurofibrillary tangles formation through amyloid protein precursor processing modulation. Although the isolated olive phytochemicals exerted lower cholinesterase inhibitory activity, OL demonstrated high inhibitory activity in the cholinergic tests evaluated. The mechanisms underlying these protective effects may be associated with decreased neuroinflammation and oxidative stress via NF-κB and Nrf2 modulation, respectively. Despite the limited research, evidence indicates that OL consumption promotes autophagy and restores loss of proteostasis, which was reflected in lower toxic protein aggregation in AD models. Therefore, olive phytochemicals may be a promising tool as an adjuvant in the treatment of AD. metadata Romero-Márquez, Jose M. and Forbes-Hernández, Tamara Y. and Navarro-Hortal, María D. and Quirantes-Piné, Rosa and Grosso, Giuseppe and Giampieri, Francesca and Lipari, Vivian and Sánchez-González, Cristina and Battino, Maurizio and Quiles, José L. mail UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, francesca.giampieri@uneatlantico.es, vivian.lipari@uneatlantico.es, UNSPECIFIED, maurizio.battino@uneatlantico.es, jose.quiles@uneatlantico.es (2023) Molecular Mechanisms of the Protective Effects of Olive Leaf Polyphenols against Alzheimer’s Disease. International Journal of Molecular Sciences, 24 (5). p. 4353. ISSN 1422-0067

Article Subjects > Nutrition Europe University of Atlantic > Research > Scientific Production
Ibero-american International University > Research > Scientific Production
Universidad Internacional do Cuanza > Research > Articles and books
Cerrado Inglés Inflammatory bowel disease (IBD) patients are at substantially higher risk of colorectal cancer (CRC) and IBD-associated CRC accounts for roughly 10-15% of the annual mortality in IBD patients. IBD-related CRC also affects younger patients if compared with sporadic CRC, with a 5-year survival rate of 50%. Regardless of medical therapies, the persistent inflammation state characterizing IBD raises the risk for precancerous changes and CRC, with additional input from several elements including genetic and environmental risk factors, IBD-associated comorbidities, intestinal barrier disfunction, and gut microbiota modifications. It is well known that nutritional habits and dietary bioactive compounds can influence IBD-associated inflammation, microbiome abundance and composition, oxidative stress balance, and gut permeability. In addition, in the last years, results from broad epidemiological and experimental studies have associated certain foods or nutritional patterns with the risk of colorectal neoplasia. Here we review the possible role of nutrition in the prevention of IBD-related CRC, focusing specifically on human studies. In conclusion it emerges that nutritional interventions based on healthy, nutrient-dense dietary patterns characterized by a high intake of fiber, vegetables, fruit, Omega-3 PUFAs, and low amount of animal proteins, processed foods and alcohol, combined with probiotic supplementation have the potential of reducing IBD-activity and preventing the risk of IBD-related CRC through different mechanisms, suggesting that targeted nutritional interventions may represent a novel promising approach for the prevention and management of IBD-associated CRC. metadata Cassotta, Manuela and Cianciosi, Danila and De Giuseppe, Rachele and Navarro-Hortal, Maria Dolores and Diaz, Yasmany Armas and Forbes-Hernández, Tamara Yuliett and Tutusaus, Kilian and Pascual Barrera, Alina Eugenia and Grosso, Giuseppe and Xiao, Jianbo and Battino, Maurizio and Giampieri, Francesca mail manucassotta@gmail.com, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, kilian.tutusaus@uneatlantico.es, alina.pascual@unini.edu.mx, UNSPECIFIED, UNSPECIFIED, maurizio.battino@uneatlantico.es, francesca.giampieri@uneatlantico.es (2023) Possible role of nutrition in the prevention of Inflammatory Bowel Disease-related colorectal cancer: a focus on human studies. Nutrition. p. 111980. ISSN 08999007

Article Subjects > Biomedicine
Subjects > Engineering
Subjects > Nutrition
Europe University of Atlantic > Research > Scientific Production
Ibero-american International University > Research > Scientific Production
Ibero-american International University > Research > Scientific Production
Universidad Internacional do Cuanza > Research > Articles and books
Cerrado Inglés Obesity and overweight has increased in the last year and has become a pandemic disease, the result of sedentary lifestyles and unhealthy diets rich in sugars, refined starches, fats and calories. Machine learning (ML) has proven to be very useful in the scientific community, especially in the health sector. With the aim of providing useful tools to help nutritionists and dieticians, research focused on the development of ML and Deep Learning (DL) algorithms and models is searched in the literature. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) protocol has been used, a very common technique applied to carry out revisions. In our proposal, 17 articles have been filtered in which ML and DL are applied in the prediction of diseases, in the delineation of treatment strategies, in the improvement of personalized nutrition and more. Despite expecting better results with the use of DL, according to the selected investigations, the traditional methods are still the most used and the yields in both cases fluctuate around positive values, conditioned by the databases (transformed in each case) to a greater extent than by the artificial intelligence paradigm used. Conclusions: An important compilation is provided for the literature in this area. ML models are time-consuming to clean data, but (like DL) they allow automatic modeling of large volumes of data which makes them superior to traditional statistics. metadata Ferreras, Antonio and Sumalla Cano, Sandra and Martínez-Licort, Rosmeri and Elío Pascual, Iñaki and Tutusaus, Kilian and Prola, Thomas and Vidal Mazón, Juan Luis and Sahelices, Benjamín and de la Torre Díez, Isabel mail UNSPECIFIED, sandra.sumalla@uneatlantico.es, UNSPECIFIED, inaki.elio@uneatlantico.es, kilian.tutusaus@uneatlantico.es, thomas.prola@uneatlantico.es, juanluis.vidal@uneatlantico.es, UNSPECIFIED, UNSPECIFIED (2023) Systematic Review of Machine Learning applied to the Prediction of Obesity and Overweight. Journal of Medical Systems, 47 (1). ISSN 1573-689X

2022

Article Subjects > Nutrition Europe University of Atlantic > Research > Scientific Production
Ibero-american International University > Research > Scientific Production
Universidad Internacional do Cuanza > Research > Articles and books
Abierto Inglés Age-related macular degeneration (AMD) is a serious degenerative disease affecting the eyes, and is the main cause of severe vision loss among people >55 years of age in developed countries. Its onset and progression have been associated with several genetic and lifestyle factors, with diet appearing to play a pivotal role in the latter. In particular, dietary eating patterns rich in plant foods have been shown to lower the risk of developing the disease, and to decrease the odds of progressing to more advanced stages in individuals already burdened with early AMD. We systematically reviewed the literature to analyse the relationship between the adherence to a Mediterranean diet, a mainly plant-based dietary pattern, and the onset/progression of AMD. Eight human observational studies were analysed. Despite some differences, they consistently indicate that higher adherence to a Mediterranean eating pattern lowers the odds of developing AMD and decreases the risk of progression to more advanced stages of the disease, establishing the way for preventative measures emphasizing dietary patterns rich in plant-foods metadata Gastaldello, Annalisa and Giampieri, Francesca and Quiles, José L. and Navarro-Hortal, María D. and Aparicio Obregón, Silvia and García Villena, Eduardo and Tutusaus, Kilian and De Giuseppe, Rachele and Grosso, Giuseppe and Cianciosi, Danila and Forbes-Hernández, Tamara Y. and Nabavi, Seyed M. and Battino, Maurizio mail UNSPECIFIED, francesca.giampieri@uneatlantico.es, jose.quiles@uneatlantico.es, UNSPECIFIED, silvia.aparicio@uneatlantico.es, eduardo.garcia@uneatlantico.es, kilian.tutusaus@uneatlantico.es, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, maurizio.battino@uneatlantico.es (2022) Adherence to the Mediterranean-Style Eating Pattern and Macular Degeneration: A Systematic Review of Observational Studies. Nutrients, 14 (10). p. 2028. ISSN 2072-6643

Revista Subjects > Nutrition Europe University of Atlantic > Research > Scientific Magazines
Ibero-american International University > Research > Scientific Magazines
Ibero-american International University > Research > Scientific Magazines
Universidad Internacional do Cuanza > Research > Scientific Magazines
Fundación Universitaria Internacional de Colombia > Research > Scientific Magazines
Abierto Inglés La revista MLS Health and Nutrition Research nace como una publicación semestral con el objetivo de publicar artículos originales de investigación y de revisión tanto en áreas básicas como aplicadas y metodológicas que supongan una contribución científica al progreso de cualquier ámbito de la salud y nutrición como objetivo principal. Los artículos incluidos en esta revista se publican en español, portugués e inglés. La vocación internacional de esta revista promueve la difusión del conocimiento en sus diferentes áreas. metadata UNSPECIFIED mail mls@devnull.funiber.org (2022) MLS Health and Nutrition Research. [Revista]

Article Subjects > Biomedicine
Subjects > Nutrition
Europe University of Atlantic > Research > Scientific Production
Fundación Universitaria Internacional de Colombia > Research > Scientific Production
Ibero-american International University > Research > Scientific Production
Ibero-american International University > Research > Scientific Production
Universidad Internacional do Cuanza > Research > Articles and books
Cerrado Inglés Cactus has been used in traditional folk medicine because of its role in treating a number of diseases and conditions. Prickly pear fruit is an excellent source of secondary metabolites (i.e., betalains, flavonoids, and ascorbic acid) with health-promoting properties against many common human diseases, including diabetes, hypertension, hypercholesterolemia, rheumatic pain, gastric mucosa diseases and asthma. In addition, prickly pears are potential candidates for the development of low-cost functional foods because they grow with low water requirements in arid regions of the world. This review describes the main bioactive compounds found in this fruit and shows the in vitro and some clinical studies about the fruit of most important cactus (Opuntia ficus-indica) and its relationship with some chronic diseases. Even though a lot of effort have been done to study the relationship between this fruit and the human health, more studies on Opuntia ficus-indica could help better understand its pharmacological mechanism of action to provide clear scientific evidence to explain its traditional uses, and to identify its therapeutic potential in other diseases. metadata Armas Diaz, Yasmany and Machì, Michele and Salinari, Alessia and Mazas Pérez-Oleaga, Cristina and Martínez López, Nohora Milena and Briones Urbano, Mercedes and Cianciosi, Danila mail UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, cristina.mazas@uneatlantico.es, nohora.martinez@uneatlantico.es, mercedes.briones@uneatlantico.es, UNSPECIFIED (2022) Prickly pear fruits from "Opuntia ficus-indica" varieties as a source of potential bioactive compounds in the Mediterranean diet. Mediterranean Journal of Nutrition and Metabolism, 15 (4). pp. 581-592. ISSN 1973798X

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Influence of E-learning training on the acquisition of competences in basketball coaches in Cantabria

The main aim of this study was to analyse the influence of e-learning training on the acquisition of competences in basketball coaches in Cantabria. The current landscape of basketball coach training shows an increasing demand for innovative training models and emerging pedagogies, including e-learning-based methodologies. The study sample consisted of fifty students from these courses, all above 16 years of age (36 males, 14 females). Among them, 16% resided outside the autonomous community of Cantabria, 10% resided more than 50 km from the city of Santander, 36% between 10 and 50 km, 14% less than 10 km, and 24% resided within Santander city. Data were collected through a Google Forms survey distributed by the Cantabrian Basketball Federation to training course students. Participation was voluntary and anonymous. The survey, consisting of 56 questions, was validated by two sports and health doctors and two senior basketball coaches. The collected data were processed and analysed using Microsoft® Excel version 16.74, and the results were expressed in percentages. The analysis revealed that 24.60% of the students trained through the e-learning methodology considered themselves fully qualified as basketball coaches, contrasting with 10.98% of those trained via traditional face-to-face methodology. The results of the study provide insights into important characteristics that can be adjusted and improved within the investigated educational process. Moreover, the study concludes that e-learning training effectively qualifies basketball coaches in Cantabria.

Producción Científica

Josep Alemany Iturriaga mail josep.alemany@uneatlantico.es, Álvaro Velarde-Sotres mail alvaro.velarde@uneatlantico.es, Javier Jorge mail , Kamil Giglio mail ,

Alemany Iturriaga

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Ultra-Wide Band Radar Empowered Driver Drowsiness Detection with Convolutional Spatial Feature Engineering and Artificial Intelligence

Driving while drowsy poses significant risks, including reduced cognitive function and the potential for accidents, which can lead to severe consequences such as trauma, economic losses, injuries, or death. The use of artificial intelligence can enable effective detection of driver drowsiness, helping to prevent accidents and enhance driver performance. This research aims to address the crucial need for real-time and accurate drowsiness detection to mitigate the impact of fatigue-related accidents. Leveraging ultra-wideband radar data collected over five minutes, the dataset was segmented into one-minute chunks and transformed into grayscale images. Spatial features are retrieved from the images using a two-dimensional Convolutional Neural Network. Following that, these features were used to train and test multiple machine learning classifiers. The ensemble classifier RF-XGB-SVM, which combines Random Forest, XGBoost, and Support Vector Machine using a hard voting criterion, performed admirably with an accuracy of 96.6%. Additionally, the proposed approach was validated with a robust k-fold score of 97% and a standard deviation of 0.018, demonstrating significant results. The dataset is augmented using Generative Adversarial Networks, resulting in improved accuracies for all models. Among them, the RF-XGB-SVM model outperformed the rest with an accuracy score of 99.58%.

Producción Científica

Hafeez Ur Rehman Siddiqui mail , Ambreen Akmal mail , Muhammad Iqbal mail , Adil Ali Saleem mail , Muhammad Amjad Raza mail , Kainat Zafar mail , Aqsa Zaib mail , Sandra Dudley mail , Jon Arambarri mail jon.arambarri@uneatlantico.es, Ángel Gabriel Kuc Castilla mail , Furqan Rustam mail ,

Siddiqui

<a href="/12749/1/fnut-11-1083759.pdf" class="ep_document_link"><img class="ep_doc_icon" alt="[img]" src="/style/images/fileicons/text.png" border="0"/></a>

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From by-products to new application opportunities: the enhancement of the leaves deriving from the fruit plants for new potential healthy products

In the last decades, the world population and demand for any kind of product have grown exponentially. The rhythm of production to satisfy the request of the population has become unsustainable and the concept of the linear economy, introduced after the Industrial Revolution, has been replaced by a new economic approach, the circular economy. In this new economic model, the concept of “the end of life” is substituted by the concept of restoration, providing a new life to many industrial wastes. Leaves are a by-product of several agricultural cultivations. In recent years, the scientific interest regarding leaf biochemical composition grew, recording that plant leaves may be considered an alternative source of bioactive substances. Plant leaves’ main bioactive compounds are similar to those in fruits, i.e., phenolic acids and esters, flavonols, anthocyanins, and procyanidins. Bioactive compounds can positively influence human health; in fact, it is no coincidence that the leaves were used by our ancestors as a natural remedy for various pathological conditions. Therefore, leaves can be exploited to manufacture many products in food (e.g., being incorporated in food formulations as natural antioxidants, or used to create edible coatings or films for food packaging), cosmetic and pharmaceutical industries (e.g., promising ingredients in anti-aging cosmetics such as oils, serums, dermatological creams, bath gels, and other products). This review focuses on the leaves’ main bioactive compounds and their beneficial health effects, indicating their applications until today to enhance them as a harvesting by-product and highlight their possible reuse for new potential healthy products.

Producción Científica

Lucia Regolo mail , Francesca Giampieri mail francesca.giampieri@uneatlantico.es, Maurizio Battino mail maurizio.battino@uneatlantico.es, Yasmany Armas Diaz mail , Bruno Mezzetti mail , Maria Elexpuru Zabaleta mail maria.elexpuru@uneatlantico.es, Cristina Mazas Pérez-Oleaga mail cristina.mazas@uneatlantico.es, Kilian Tutusaus mail kilian.tutusaus@uneatlantico.es, Luca Mazzoni mail ,

Regolo

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Efficient deep learning-based approach for malaria detection using red blood cell smears

Malaria is an extremely malignant disease and is caused by the bites of infected female mosquitoes. This disease is not only infectious among humans, but among animals as well. Malaria causes mild symptoms like fever, headache, sweating and vomiting, and muscle discomfort; severe symptoms include coma, seizures, and kidney failure. The timely identification of malaria parasites is a challenging and chaotic endeavor for health staff. An expert technician examines the schematic blood smears of infected red blood cells through a microscope. The conventional methods for identifying malaria are not efficient. Machine learning approaches are effective for simple classification challenges but not for complex tasks. Furthermore, machine learning involves rigorous feature engineering to train the model and detect patterns in the features. On the other hand, deep learning works well with complex tasks and automatically extracts low and high-level features from the images to detect disease. In this paper, EfficientNet, a deep learning-based approach for detecting Malaria, is proposed that uses red blood cell images. Experiments are carried out and performance comparison is made with pre-trained deep learning models. In addition, k-fold cross-validation is also used to substantiate the results of the proposed approach. Experiments show that the proposed approach is 97.57% accurate in detecting Malaria from red blood cell images and can be beneficial practically for medical healthcare staff.

Producción Científica

Muhammad Mujahid mail , Furqan Rustam mail , Rahman Shafique mail , Elizabeth Caro Montero mail elizabeth.caro@uneatlantico.es, Eduardo René Silva Alvarado mail eduardo.silva@funiber.org, Isabel de la Torre Diez mail , Imran Ashraf mail ,

Mujahid

<a class="ep_document_link" href="/12751/1/s12874-024-02249-8.pdf"><img class="ep_doc_icon" alt="[img]" src="/style/images/fileicons/text.png" border="0"/></a>

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Feature group partitioning: an approach for depression severity prediction with class balancing using machine learning algorithms

In contemporary society, depression has emerged as a prominent mental disorder that exhibits exponential growth and exerts a substantial influence on premature mortality. Although numerous research applied machine learning methods to forecast signs of depression. Nevertheless, only a limited number of research have taken into account the severity level as a multiclass variable. Besides, maintaining the equality of data distribution among all the classes rarely happens in practical communities. So, the inevitable class imbalance for multiple variables is considered a substantial challenge in this domain. Furthermore, this research emphasizes the significance of addressing class imbalance issues in the context of multiple classes. We introduced a new approach Feature group partitioning (FGP) in the data preprocessing phase which effectively reduces the dimensionality of features to a minimum. This study utilized synthetic oversampling techniques, specifically Synthetic Minority Over-sampling Technique (SMOTE) and Adaptive Synthetic (ADASYN), for class balancing. The dataset used in this research was collected from university students by administering the Burn Depression Checklist (BDC). For methodological modifications, we implemented heterogeneous ensemble learning stacking, homogeneous ensemble bagging, and five distinct supervised machine learning algorithms. The issue of overfitting was mitigated by evaluating the accuracy of the training, validation, and testing datasets. To justify the effectiveness of the prediction models, balanced accuracy, sensitivity, specificity, precision, and f1-score indices are used. Overall, comprehensive analysis demonstrates the discrimination between the Conventional Depression Screening (CDS) and FGP approach. In summary, the results show that the stacking classifier for FGP with SMOTE approach yields the highest balanced accuracy, with a rate of 92.81%. The empirical evidence has demonstrated that the FGP approach, when combined with the SMOTE, able to produce better performance in predicting the severity of depression. Most importantly the optimization of the training time of the FGP approach for all of the classifiers is a significant achievement of this research.

Producción Científica

Tumpa Rani Shaha mail , Momotaz Begum mail , Jia Uddin mail , Vanessa Yélamos Torres mail vanessa.yelamos@funiber.org, Josep Alemany Iturriaga mail josep.alemany@uneatlantico.es, Imran Ashraf mail , Md. Abdus Samad mail ,

Shaha