Chronotype and Cancer: Emerging Relation Between Chrononutrition and Oncology from Human Studies
Artículo
Materias > Biomedicina
Materias > Alimentación
Universidad Europea del Atlántico > Investigación > Producción Científica
Fundación Universitaria Internacional de Colombia > Investigación > Producción Científica
Universidad Internacional Iberoamericana México > Investigación > Producción Científica
Universidad Internacional do Cuanza > Investigación > Artículos y libros
Universidad de La Romana > Investigación > Producción Científica
Abierto
Inglés
Fasting–feeding timing is a crucial pattern implicated in the regulation of daily circadian rhythms. The interplay between sleep and meal timing underscores the importance of maintaining circadian alignment in order to avoid creating a metabolic environment conducive to carcinogenesis following the molecular and systemic disruption of metabolic performance and immune function. The chronicity of such a condition may support the initiation and progression of cancer through a variety of mechanisms, including increased oxidative stress, immune suppression, and the activation of proliferative signaling pathways. This review aims to summarize current evidence from human studies and provide an overview of the potential mechanisms underscoring the role of chrononutrition (including time-restricted eating) on cancer risk. Current evidence shows that the morning chronotype, suggesting an alignment between physiological circadian rhythms and eating timing, is associated with a lower risk of cancer. Also, early time-restricted eating and prolonged nighttime fasting were also associated with a lower risk of cancer. The current evidence suggests that the chronotype influences cancer risk through cell cycle regulation, the modulation of metabolic pathways and inflammation, and gut microbiota fluctuations. In conclusion, although there are no clear guidelines on this matter, emerging evidence supports the hypothesis that the role of time-related eating (i.e., time/calorie-restricted feeding and intermittent/periodic fasting) could potentially lead to a reduced risk of cancer.
metadata
Godos, Justyna; Currenti, Walter; Ferri, Raffaele; Lanza, Giuseppe; Caraci, Filippo; Frias-Toral, Evelyn; Guglielmetti, Monica; Ferraris, Cinzia; Lipari, Vivian; Carvajal Altamiranda, Stefanía; Galvano, Fabio; Castellano, Sabrina y Grosso, Giuseppe
mail
SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, vivian.lipari@uneatlantico.es, stefania.carvajal@uneatlantico.es, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR
(2025)
Chronotype and Cancer: Emerging Relation Between Chrononutrition and Oncology from Human Studies.
Nutrients, 17 (3).
p. 529.
ISSN 2072-6643
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Texto
nutrients-17-00529.pdf Available under License Creative Commons Attribution. Descargar (703kB) |
Resumen
Fasting–feeding timing is a crucial pattern implicated in the regulation of daily circadian rhythms. The interplay between sleep and meal timing underscores the importance of maintaining circadian alignment in order to avoid creating a metabolic environment conducive to carcinogenesis following the molecular and systemic disruption of metabolic performance and immune function. The chronicity of such a condition may support the initiation and progression of cancer through a variety of mechanisms, including increased oxidative stress, immune suppression, and the activation of proliferative signaling pathways. This review aims to summarize current evidence from human studies and provide an overview of the potential mechanisms underscoring the role of chrononutrition (including time-restricted eating) on cancer risk. Current evidence shows that the morning chronotype, suggesting an alignment between physiological circadian rhythms and eating timing, is associated with a lower risk of cancer. Also, early time-restricted eating and prolonged nighttime fasting were also associated with a lower risk of cancer. The current evidence suggests that the chronotype influences cancer risk through cell cycle regulation, the modulation of metabolic pathways and inflammation, and gut microbiota fluctuations. In conclusion, although there are no clear guidelines on this matter, emerging evidence supports the hypothesis that the role of time-related eating (i.e., time/calorie-restricted feeding and intermittent/periodic fasting) could potentially lead to a reduced risk of cancer.
Tipo de Documento: | Artículo |
---|---|
Notas: | chronotype; sleep; time-restricted eating; circadian rhythm; metabolic dysregulation; gut microbiota; cancer |
Clasificación temática: | Materias > Biomedicina Materias > Alimentación |
Divisiones: | Universidad Europea del Atlántico > Investigación > Producción Científica Fundación Universitaria Internacional de Colombia > Investigación > Producción Científica Universidad Internacional Iberoamericana México > Investigación > Producción Científica Universidad Internacional do Cuanza > Investigación > Artículos y libros Universidad de La Romana > Investigación > Producción Científica |
Depositado: | 20 Feb 2025 23:30 |
Ultima Modificación: | 20 Feb 2025 23:30 |
URI: | https://repositorio.unic.co.ao/id/eprint/16759 |
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